B.A., Virginia Military Institute, Lexington, Virginia
M.S., Virginia Polytechnic Institute, Blacksburg, Virginia
Ph.D., State University of New York School of Medicine, Buffalo, New York

Cardiac cellular electrophysiology and cardiac intracellular pH regulation.

NIH MERIT Award 2003
Appointed Visiting Professor in the Department of Physiology, Anatomy and Genetics at Oxford University, UK, 2006

McNary TG, Spitzer KW, Holloway H, Bridge JHB, Kohl P, Sachse FB. Mechanical modulation of the transverse tubular system of ventricular cardiomyocytes. Prog Biophys Mol Biol. 2012;110:218-225    online

Ajiro T, Saegusa N, Giles WR, Stafforini DM, Spitzer KW. Platelet-activating factor stimulates sodium-hydrogen exchange in ventricular myocyes. Am J Physiol Heart & Circ Physiol. 2011;In press    online

Saegusa N, Moorhouse E, Vaughan-Jones RD, Spitzer KW. Influence of pH on Ca2+ current and its control of electrical and Ca2+ signaling in ventricular myocytes. J Gen Physio. 2011;138(5):537-559    online

Barry WH, Zhang XQ, Halkos ME, Vinten-Johansen J, Saegusa N, Spitzer KW, Matsuoka N, Sheets M, Rao NV, Kennedy T. Non-Anticoagulant Heparin Reduces Myocyte Na+ and Ca2+ Loading During Simulated Ischemia and Decreases Reperfusion Injury. Am. J. Physiol.. 2010;298:H102-H111    online

Jou CJ, Spitzer KW, Tristani-Firouzi M. Blebbistatin effectively uncouples the excitation-contraction process in zebrafish embryonic heart. Cell Physiol Biochem. 2010;25(4-5):419-424    online

Swietach P, Spitzer KW, Vaughan-Jones RD. Modeling calcium waves in cardiac myocytes importance of calcium diffusion. Front Biosci. 2010;15:661-680    online

Warren M, Spitzer KW, Steadman BW, Rees TD, Venable P, Taylor T, Shibayama J, Yan P, Wuskell JP, Loew LM, Zaitsev AV. High precision recording of the action potential in isolated cardiomyocytes using the near-infrared fluorescent dye di-4-ANBDQBS. Am J Physiol Heart Circ Physiol. 2010;299(4):H271-H1281    online

Vaughan-Jones RD, Spitzer KW, Swietach P. Intracellular pH regulation in heart. J Mol Cell Cardiol. 2009;46(3):318-331    online

Swietach P, Rossini A, Spitzer KW, Vaughan-Jones RD. Ca2+ -mobility in the sarcoplasmic reticulum of ventricular myocytes is low. Biophys J. 2008;95(3):1412-1427    online

Arnaout R, Ferrer T, Huisken J, Spitzer KW, Stainier DY, Tristani-Firouzi M. Zebrafish model for human long QT syndrome. Proc Natl Acad Sci U S A. 2007;104(27):11316-11321