Bioengineering/Physiology 6000
System Physiology I:
Cardiovascular, Respiratory, and Renal Systems
Spring Semester, 2008

Version: March 17, 2008

Essentials:
Class times: Monday, Wednesday, and Friday, 9:40-10:30
Classroom: MEB 2325
Labs: Thursday, 2:00-5:00 in MEB 1480

Instructors:

Name Phone Email Office Office Hours
Rob MacLeod (RM) 587-9511 macleod@cvrti.utah.edu 3476 MEB by appointment
TA: Cris Lapierre TBA crislapi@abl.med.utah.edu Anesthes. by appointment

(See also www.bioen.utah.edu/faculty.html for more information on Bioengineering faculty)

Text:

Eckert Animal Physiology, 5th ed., D. Randall, W. Burggren, and K. French. W.H. Freeman and Co., 2001. Additional readings may be assigned throughout the course.

Grading:

Laboratory Schedule:

Lab # Date Topic
1 Th 17 Jan Dissection of the bovine heart/lungs
  Th 31 Jan Open (MATLAB?)
2 Th 14 Feb Regulation of heart rate and contraction (frog)
3 Th 28 Feb ECG
4 Th 13 Mar ECG Simulation Lab
5 Th 27 Mar Exercise and blood pressure
6 Th 10 Apr Pulmonary function

Lectures and Reading Material (next page)

* mathend000# (CV=cardiovascular, PR=pulmonary/respiratory, RE=renal) mathend000# Chapter numbers from Text and LB = Lecture block number

# Date Inst. Topic* mathend000# Reading mathend000#
1 Mo 7 Jan RM Intro to animal physiology I 1:1-7/LB 1
2 We 9 Jan RM Project description and Everest video  
3 Fr 11 Jan RM Intro to animal physiology II 1:7-14/LB 1
4 Mo 14 Jan RM Intro to animal physiology III 1:7-14/LB 1
5 We 16 Jan RM Experimental techniques I 2:19-40/LB 2
Lab 1 Th 17 Jan Dissection of the bovine heart/lungs
6 Fr 19 Jan RM Review of Lab  
      Resting potentials 4:99-109, 5:118-132/LB 3
  Mo 21 Jan Martin Luther King Jr. Day Holiday
7 We 23 Jan RM Action potentials I 12:479-480/LB 3
8 Fr 25 Jan RM Action potentials II Notes LB 3
9 Mo 28 Jan RM Simulation of cell action potential Notes LB 4
10 We 30 Jan RM Pacemakers and Excitation/Contraction Coupling Notes LB 3, 12:477-479
  Th 31 Jan Open Lab day (MATLAB discussion?)
11 Fr 1 Feb RM Tissue Electrophysiology I 12:479-480/LB 5
12 Mo 4 Feb RM Tissue Electrophysiology II 12:479-480/LB 5
13 We 6 Feb RM Arrhythmias LB 5
14 Fr 8 Feb RM Circulation & Heart as a pump 12:478-486/LB 7
15 Mo 11 Feb RM Heart Rate Regulation 12:477-479
16 We 13 Feb RM Heart Rate Regulation, Frog lab 12:477-479
Lab 2 Th 14 Feb Regulation of heart rate and contraction (frog)
17 Fr 15 Feb RM Lab discussion & Electrocardiogram I LB 8
  Mo 18 Feb President's Day Holiday
18 We 20 Feb RM Electrocardiogram II LB 8
  Fr 22 Feb Midterm Exam #1
19 Mo 25 Feb RM ECG lead systems LB 8
20 We 27 Mar RM ECG lead systems LB 8
Lab 3 Th 28 Feb ECG Lab
21 Fr 29 Feb RM Lab discussion & Hemodynamics 12:495-505/LB 9
22 Mo 3 Mar RM Overview of CV System 12:473-477/LB 6
23 We 4 Mar RM Overview of CV System 12:473-477/LB 6
24 Fr 7 Mar RM Hemodynamics & Arterial System 12:495-505/LB 9,10
25 Mo 10 Mar RM Hemodynamics & Arterial System 12:495-505/LB 9,10
26 We 12 Mar RM Simulation of cardiac electrophysiology Lab
Lab 4 Th 13 Mar ECG Simulation Lab
27 Fr 14 Mar RM Lab review and control of blood pressure 12:512-523, LB 12
March 17-21, Spring Break
25 Mo 24 Mar RM Regulation of circulation 12:506-511, LB 11
26 We 26 Mar RM Regulation during exercise and blood pressure 12:512-523/LB 12
Lab 5 27 Mar Exercise and blood pressure
27 Fr 28 Mar RM Capillaries and microcirculation I 12:506-511/LB 11
28 Mo 31 Mar RM O2 mathend000# and CO2 mathend000# transport and pH regulation 13:541-544/LB 13, 14
29 We 2 Apr RM O2 mathend000# and CO2 mathend000# transport and pH regulation 13:541-544/LB 13, 14
  Fr 4 Apr Midterm Exam #2
30 Mo 7 Apr RM Mechanics of ventilation 13:545-555/LB 15
31 We 9 Apr RM Ventilation and Control of Respiration 13:545-568/LB 15, 16
Lab 6 Th 10 Apr Pulmonary function
32 Fr 11 Apr RM Lab review & Intro to Renal System  
33 Mo 14 Apr RM Osmotic balance 14:579-587/LB 17
34 We 16 Apr RM Osmoregulation 14:588-593/LB 17
35 Fr 18 Apr Class canceled
36 Mo 21 Apr RM The kidney: proximal tubule 13:593-615/LB 18
37 We 23 Apr RM The kidney: distal tubule 13:593-628/LB 18
  We 30 Apr 8:00-10:00, Final Exam

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