Bioengineering/Physiology 6000:
System Physiology I: Cardiovascular,
Respiratory, and Renal Systems

Spring 2008 Deadlines

Here are the current (and past) deadlines for the class.

Monday, January 7: first day of class
Tuesday, January 18, 2:00: MATLAB tutorial in MEB 1480
Wednesday, January 19: Homewoerk #1 due (5:00 pm by email)
Thursday, January 31: Lab report #1 (dissection) due
Thursday, February 7: Homework assignment #2
Friday, February 15: Homework assignment #3
Friday, February 22: Midterm #1
Thursday, February 28: Lab report #2 (frog lab) due
Friday, March 14: Proposal for term paper due
Monday, March 16: Lab report #3 (ECG lab) due
Thursday, March 27: Lab report #4 (ECG Simulation) due
Friday, March 28: outline for term paper due
Wednesday, April 16: term paper due
Friday, April 4: Midterm #2
Thursday, April 10: Lab #5 (Exercise) report due
Thursday, April 24: Lab #6 (Respiration) report due
Wednesday, Apr 30, 8:00--10:00 final exam (in regular classroom)

Important Course Information

If you have questions about the course please contact Rob MacLeod for any questions.

Please sign up for the class mailing list by sending an email to majordomo@sci.utah.edu
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Still slightly tentative but always-dynamic Course Syllabus , also available in PDF (Acrobat) format
Midterm #1 study topics (February 22, 2008).
Midterm #2 study topics (April 4, 2007). Also available as PDF document
Midterm #2 Comments
Study topics for the final. Also available as PDF document

Course Lecture Notes

Lecture block 1 (Rob MacLeod): Introduction
- PDF for printing (3.5 MB)
Lecture block 3 (Rob MacLeod): Cardiac Cellular Electrophysiology
- Part 1: the basics PDF (11 MB)
- Part 2: EC coupling and pacemakers (0.5 MB)
- Review article on EC Coupling by Don Bers.
Lecture block 4 (Rob MacLeod): Simulation of cardiac action potential
- slides in PDF (1.5 MB)
Lecture block 5 (Rob MacLeod): Cadiac Tissue Structure and Function
- slides in PDF (18 MB)
Lecture block 7 (Rob MacLeod): Whole Heart Physiology
- PDF for printing (7 MB) and
- Normal cardiac structure and EC coupling (5.2 MB)
- Effect of hypertension on EC coupling (3.4 MB)
- Effect of dilated cardiomypoathy on EC coupling (3.4 MB)
Lecture block 8: The ECG
- PDF for printing in color (3.7 MB)
Lecture block 6 (Rob MacLeod): Intro to Circulation System
- PDF for printing (1.6 MB)
Lecture block 9: Hemodynamics
- PDF for printing (1.5 MB)
Lecture block 10: Arteries and Veins
- PDF for printing (3 MB)
Lecture block 12: Control of circulation
- PDF for printing (2 MB)
Lecture block 11: Microcirculation
- PDF for printing (3.5 MB)
Lecture block 13: Gases and Gas Transport
- PDF for printing color (3.5 MB)
Lecture block 15: Lung structure and function
- PDF for printing color (5.5 MB)
- paper by Mitzner about the utility of airway smooth muscle.
Lecture block 16: Control of Ventilation
- PDF for printing color (3.7 MB)
Lecture block 17: Osmotic Balance
- PDF for printing color (6 MB)
Lecture block 18: The Kidney
- PDF for printing color (18 MB)

Laboratory Exercises

Lab # Date Topic/Description Links/Data/Comments

1 Th 17 Jan Dissection of bovine heart/lungs (also in pdf version ) Comments on lab reports (pdf)

2 Th 14 Feb Regulation of heart rate and contraction (frog) (also in pdf version ) Comments on lab reports (pdf)

3 Th 28 Feb ECG lab (also in PDF version)
4 Th 13 Mar Simulation Lab, ECG simulation (also in PDF version)

5 Th 27 Mar Exercise and blood pressure (also in PDF version)

6 Th 10 Apr Pulmonary function (also in PDF version)

Homework/Lab Assignments

Ground rules and tips for the homework assignments (applies also to lab reports and the term paper).

Link to MATLAB information

The Assignments

Homework Assignment #1 MATLAB review, due Friday, Jan 18, 5:00 pm.
- Data for for the assignment Make sure to right-click (control-click on the Mac) this link and save the linked file to your computer.
Homework Assignment #2 Simulation of cardiac action potentials, due Thursday, February 7
- Instructions for the assignment, also available in PDF format.
- Background information in PDF format.
- Tarred archive file for the Matlab code for Homework Assignment.
- Directory containing all the individual Matlab files--same content as above, but you must download file by file.
- Links to the original Hodgkin and Huxley paper and also a tribute to this research.
- Comments on the assignment
Home Assignment #3 Signal processing in MATLAB, due Friday, February 15.
- Assignment in PDF
- Data file ecg-24310.rdata (right-click or control-click to save file)
- Data file ecg-2438.rdata (right-click or control-click to save file)

Semester Project

There is a term project for the course that is due during the last week of classes. Note that the outline for the project is due just after the March break.

MATLAB Info

General information
Shibaji's MATLAB presentation (from 2005)
Accompanying m-files:
- myfile.m the main program file.
- chkevod.m
- getrslt.m
- plotter.m

Additional background information.

Last modified: Fri Apr 4 09:47:40 MDT 2008

Lab #	Date	Topic/Description	Links/Data/Comments
1	Th 17 Jan	Dissection of bovine heart/lungs (also in pdf version )	Comments on lab reports (pdf)
2	Th 14 Feb	Regulation of heart rate and contraction (frog) (also in pdf version )	Comments on lab reports (pdf)
3	Th 28 Feb	ECG lab (also in PDF version)
4	Th 13 Mar	Simulation Lab, ECG simulation (also in PDF version)
5	Th 27 Mar	Exercise and blood pressure (also in PDF version)
6	Th 10 Apr	Pulmonary function (also in PDF version)

Bioengineering/Physiology 6000: System Physiology I: Cardiovascular, Respiratory, and Renal Systems